All-natural extract from American Hops
provides fast-acting, all-day relief
from ordinary aches and pains.
Gentle enough for daily use.
If you have any questions,
please don't hesitate to call our
toll free customer service line.
Our friendly agents
are ready to help you.
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Vinoprin® - All Natural Pain-Relief
Vinoprin® - Bruce G. testimonial
Vinoprin® - Amazing Health Benefits
Vinoprin® - Carmen R. testimonial
Lose Your Pain, Not Your Health
Vinoprin® is based on a pure extract from the hops plant, which is primarily grown to provide the pleasant, bitter flavor that balances the malt in beer. Hops have been used medicinally for over a thousand years, but modern super critical extraction technology allows us to isloate the pain relieving components, without the use of any toxic solvents. Contains 150mg of humulones (alpha acids) - the active anti-inflammatory components, its designed to be free of phytoestrogenic and sleep inducing compounds.
Vinoprin® works by blocking the Cox-2 enzyme, while only moderately inhibiting the Cox-1 enzyme which protects the gastrointestinal tract. Vinoprin® gives you pain relief without the harmful side effects!
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What is Vinoprin®?
All-natural extract from American Hops provides fast-acting, all-day relief from ordinary aches and pains. Gentle enough for daily use.
Fifteen years of research have culminated in all-natural supplement that can provide significant relief from ordinary aches and pains without the dangerous side effects associated with over-the-counter and prescription pain medications. Most people suffer from occasional aches and pains, but as many as 70 million US adults - an astonishing one in three - suffer from frequent pain.
When pain hits, many people turn to NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen, and naproxen. However, these drugs can have many adverse side effects.
Vinoprin® is different. It is based on a pure extract from the hops plant, which is primarily grown to provide the pleasant, bitter flavor that balances the sweetness of malt in beer. Hops have been used medicinally for over a thousand years, but modern super critical extraction technology allows us to isolate the pain relieving components, without the use of any toxic solvents.
Safety and Purity
Hops extract safety has been confirmed in both human and animal trials. Large dosages were found to be non-toxic and non-mutagenic. Vinoprin® is made from hops grown in the USA at USDA inspected farms. The extract is tested to ensure the absence of heavy metals and 73 different pesticides. Vinoprin® softgels are manufactured in the USA at ISO-c and cGMP-certified facilities. Each Vinoprin® softgel is standardized to contain at least 150mg of humulones (alpha acids), the active ingredient. In addition, small amounts of peppermint and ginger oils are added to counteract any possible GI upset. Vinoprin® is non-GMO, free of milk, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten and soy. Hops (Humulus lupulus L.) is GRAS (generally recognized as safe) as a food ingredient (21 CFR 182.20).
The Science Behind Vinoprin®
The COX Problem
Plant-Derived Anti-Inflammatory Agent
Human Clinical Trials
NSAIDs Inhibit COX
NSAIDS (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen, and naproxen are inhibitors of the Cyclooxygenase or COX enzymes, which cause pain and inflammation. Unfortunately, NSAIDS aren't selective; they inhibit both the COX-1 and COX-2 enzymes with varying intensity. So, while pain may be reduced by blocking the COX-2 enzyme, non-selective inhibition of COX-1, whose job is to protect the gastro-intestinal (GI) tract lining, can lead to dangerous side effects. Several newer drugs were developed that were more selective. But these drugs turned out to have even more severe side effects, potentially increasing the risk of heart attack and stroke. The problem was too much selectivity. By completely shutting down COX-2, these drugs may have shut down the production of blood-clotting hormones and other cardio-protective enzymes.
Whole Blood Assay Reveals Surprising Results
The William Harvey Whole Blood Assay is considered the "gold standard" for evaluating a compounds's COX activity and selectivity. The goal was to find a botanical extract that could moderately inhibit the pain causing COX-2, while only mildly inhibiting the protective COX-1. The humulones extracted from hops fit this model perfectly. The extract inhibited COX-2 strongly enough to alleviate pain, without shutting down the enzyme altogether. And it only mildly inhibited COX-1 to avoid GI problems.
The Quest to Find a Plant-Derived Anti-Inflammatory Agent
Vinoprin® contains a proprietary hops extract that is standardized to contain 150mg of humulones (alpha acids) - the active anti-inflammatory components - and designed to be free of phytoestrogenic and sleep inducing compounds. The extraction process utilizes high temperature, high pressure, liquid C02, to perform the extraction with NO toxic chemicals. During the late 1990s, several research companies began looking for natural ways to ease the pain of arthritis and other conditions. Hundreds of different botanicals were examined, and thousands of pages of scientific studies were reviewed. At the end of this painstaking process, about 20 candidates were identified for further study. All of the prospects, including higly regarded botanical agents such as curcumin and boswellia were subjected to in vitro testing to determine their anti-inflammatory potential. Of those, the hops extract was identified as having the highest chance of success.
Human Clinical Trials Confirm the Findings
These COX inhibition properties were confirmed on a group of healthy volunteers, with blood levels of COX enzymes measured over a 9 hour period. A double-blind efficacy study showed that hops extract provided significant pain relief vs. placebo to subjects suffering from pain. During the 14 day trial period, subjects were measured to have significant improvements in comfort while walking, standing, climbing stairs, and sleeping.
In-vitro testing, utilizing the standard CACO-2 cell monlayer assay indicates that there is high permeability of the hops extract, which correlates with good human oral bioavailability.
Frequently Asked Questions
How long will it take before I feel the benefits of Vinoprin®?
You will begin to feel relief in 30-60 minutes, with maximum relief in about 2 hours. For most people, the relief will last at least 9-12 hours.
What kind of pain can I use Vinoprin® for?
Vinoprin® is not a drug, and is not intended to treat any disease. However, Vinoprin® is effective for almost all normal aches and pains in any part of the body.
Are there any interactions with other medications?
There are no known interactions with any common over-the-counter medications. It is always prudent to check with your doctor if you are taking any prescription medications. Vinoprin® has not been tested for safety on pregnant or nursing women, and should not be taken.
How many Vinoprin® softgels should I take?
For normal aches and pains, take one in the morning, and an additional one in the evening if you have discomfort sleeping. For more severe aches and pains, take two at a time.
Should I take Vinoprin® with food?
Please take Vinoprin® after a meal whenever possible. The hops extracts are very bitter, and may cause heartburn or burping if taken without food. Ginger and peppermint oils are added to help settle the stomach.
Aren't hops found in beer? Is there alcohol in Vinoprin® or anything that will make me sleepy?
The active ingredients in Vinoprin® are extracted from raw, unfermented hops and contain no alcohol. An advanced process extracts only the pain relief compounds from the Hops, and eliminates all phytoestrogens and sleep inducing compounds.
Contact Us - Our Guarantee
Order with CONFIDENCE
Every bottle of Vinoprin® comes with our no-hassle money back guarantee. If you are not 100% satisfied, you can send back full or empty bottles for a full refund!
Vinomis offers a convenient, money-saving automatic reorder program that ensures you won't run out of Vinoprin®. We will automatically place a 180-softgel reorder for you every 90 days, or as often as you like. There is no obligation and you may cancel at any time. Please select the "free shipping with automatic reorder" in the order form or call customer service for additional assistance.
We would love to hear from you or assist you in purchasing.
Please call us at 1-877-4-VINOMIS (1-877-484-6664)
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Vinomis Laboratories, LLC
509 Hegner Way
Sewickley, PA 15143
Monday - Friday
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