Calorie Restriction
Calorie Restriction has been proven to be an effective means for increasing longevity. However, a person would need to consume about 25-40% fewer calories than a "normal" diet, and most people are unable or unwilling to live with the near-starvation of this regimen. In addition, the longevity benefits can be completely negated unless extreme care is taken to make sure the diet is balanced and complete. Calorie restriction has been found to activate the SIRT genes, as a means to survival. The activation of these genes slows down the aging process, and forestalls many of the diseases associated with aging.
The excitement over Resveratrol (and other polyphenols) revolves around the discovery that it activates exactly the same genes in exactly the same way as severe calorie restriction.
References:
In this study, researchers examined 28 members of the Calorie Restriction Society who had been eating a CR diet for an average of six years. Although the CR group consumed fewer calories -- averaging only about 1,800 per day -- they consumed at least 100 percent of the recommended daily amounts of protein and micronutrients. The researchers found reduction in aging markers. More...
Calorie Restriction and Resveratrol activate the SIRT pathways. This Science article shows the common connection between calorie restriction and Resveratrol and their affect on health and longevity. More...