Diabetes is a disease of sugar and fat metabolism caused by problems with insulin secretion by the pancreas, or with insulin sensitivity of the cells. Type I diabetes usually inflicts children and young adults, as the body’s immune system destroys the insulin-secreting cells in the pancreas. Type II, or adult-onset diabetes, begins when cells do not use insulin properly, and the pancreas attempts to generate more insulin and gradually loses the ability to do so.


If Americans reduced their intake of refined sugar and regularly exercised, it would cut the incidence of diabetes in the U.S. in half. Unfortunately, just the opposite is occurring. In the last 25 years, the number of newly diagnosed adults with diabetes has almost tripled to 1.4 million.

What then are the effects on diabetes from Resveratrol, Quercetin, and plant polyphenols? Scientists have shown that through their ability to decrease insulin resistance, enhance glucose’s ability to enter the cells, and weight stabilization, these polyphenols provide a complementary way to combat the disease.

In 1985, C.S. Hii and S.L. Howel, from the University of Adelaide in Australia, discovered that 2 polyphenols in Red-wine and grape juice ( &epicatechin) enhanced insulin release in rats by 44 - 70%.

In 2003, Dr. MahmoodVessal at Shiraz University in Iran showed that regenerated pancreatic cells and increased insulin release in diabetic rats. In 2004,scientists at the University of Montpellier in France used healthy animals to confirm that reduced blood sugar and decreased appetite.

In 2005, Edward Park at Canada’s Brock University discovered that can counter the effects of elevated free fatty acids, allowing the normal uptake of insulin.

In 2005, a study in Chile showed that , and several other polyphenols found in grape skins, also slowed sugar absorption in the intestines. appears to be effective in reducing the high spike in insulin that occurs when sugary food is eaten. In addition, is also a potent inhibitor of sugars in the intestine.

In 2006, Hui-Chen Sui in Taiwan showed that stimulated the uptake of glucose by liver, fat and muscle cells.

These studies on and the mechanisms of glucose, insulin, and fat metabolism, are supported by the work of Dr. David Sinclair and Dr. Joseph Baur of Harvard University from 2006 to the present.