Much research is in progress on the potential weight control properties of Resveratrol. Resveratrol has been shown to reduce the number of fat cells in laboratory mice in several studies. Researchers at the University of Ulm investigated whether Resveratrol could duplicate the effects of caloric restriction in human fat cells by altering their function or size. Other studies had previously demonstrated that Resveratrol inhibited lab mice, fed high calorie diets, from becoming obese by matching the effects of caloric restriction.
The Ulm findings were presented at The Endocrine Society's annual meeting in 2008. In their tests they saw that Resveratrol hindered pre-fat cells from increasing and from changing into mature fat cells. Resveratrol was also found to inhibit fat storage. The most intriguing discoveries were firstly, that Resveratrol decreased the creation of specific cytokines that may be linked to obesity connected disorders like diabetes, and secondly, Resveratrol activated the production of a protein called adiponectin which is known to reduce the risk of heart attacks and is decreased by the onset of obesity.
In summary, the researchers from Germany concluded that Resveratrol holds promise in the treatment of obesity and obesity related disorders such as diabetes and clogged heart arteries.
In other studies, Resveratrol has been shown to increase metabolic activity, which can go a long way towards losing weight, and maintaining a healthy weight. Resveratrol activates the SIRT genes. When they are activated, weight gain seems to be prevented, even when a high fat diet is being consumed, by inhibiting fat storage. When the body is storing fewer fat cells, the aging process can also be slowed by reducing age and obesity related conditions and diseases.
References:
Resveratrol inhibits the growth of fat cells. A 2008 study by Dr. Martin Wabitsch, a pediatric endocrinologist at the University of Ulm in Germany. In the study, laboratory tests on human cells showed that Resveratrol inhibits the number of nascent fat cells that grow into mature fat cells. More...
Resveratrol prevents fat accumulation in livers Of 'alcoholic' mice. A 2008 study at the University of South Florida found that Resveratrol reduced the amount of fat produced in the liver of mice fed alcohol and, at the same time, increased the rate at which fat within the liver is broken down. More...
Resveratrol resulted in weight reduction. Researchers from the University of Louis Pasteur, in collaboration with colleagues from Harvard and Kuopio Universities and Sirtis Pharmaceuticals, administered a dietary supplement of Resveratrol to mice in a 2006 study. The animals demonstrated a high level of endurance both during exercise and during inactivity. The Resveratrol was seen to activate a protein in the Sirtuin family and led to a reduction in weight. The study found a link between the SIRT genes
and energy expenditure. More...
