Vinoprin® One Hour Pain Relief All-Natural Pain Relief 1 bottle = 60 softgels

Why even take the health risks, when there is an All-Natural Alternative?

15 years of research have culminated in an all-natural supplement that can provide significant relief from ordinary aches and pains without the dangerous side effects associated with over-the-counter and prescription pain medications. Most people suffer from occasional aches and pains, but as many as 70 million US adults - an astonishing one in three - suffer from frequent pain.

When pain hits, many people turn to NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen, and naproxen. However, these drugs can have many adverse side effects.

Vinoprin® One Hour Pain Relief is different. It is based on a pure extract from the hops plant, which is primarily grown to provide the pleasant, bitter flavor that balances the sweetness of malt in beer. Hops have been used medicinally for over a thousand years, but modern supercritical extraction technology allows us to isolate the pain relieving components, without the use of any toxic solvents.



Lose Your Pain, Not Your Good Health








 

• All-Natural, Safe and Non-Habit Forming

• Sleep Pain Free and Wake Up Refreshed

• Relieves your Pain in Just 1 Hour

• 8 to 12 Hours of Relief

The Science Behind One Hour Pain Relief
Safety and Purity

Hops extract safety has been confirmed in both human and animal trials. Large dosages were found to be non-toxic and non-mutagenic. Vinoprin One Hour Pain Relief is made from hops grown in the USA at USDA inspected farms. The extract is tested to ensure the absence of heavy metals and 73 different pesticides. Vinoprin One Hour Pain Relief softgels are manufactured in the USA at ISO-c and cGMP-certified facilities. Each Vinoprin One Hour Pain Relief softgel is standardized to contain at least 150mg of humulones (alpha acids), the active ingredient. In addition, small amounts of peppermint and ginger oils are added to counteract any possible GI upset. Vinoprin One Hour Pain Relief is non-GMO, free of milk, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten and soy. Hops (Humulus lupulus L.) is GRAS (generally recognized as safe) as a food ingredient (21 CFR 182.20).

The Cox Problem

NSAIDs Inhibit COX

NSAIDS (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen, and naproxen are inhibitors of the Cyclooxygenase or COX enzymes, which cause pain and inflammation. Unfortunately, NSAIDS aren't selective; they inhibit both the COX-1 and COX-2 enzymes with varying intensity. So, while pain may be reduced by blocking the COX-2 enzyme, non-selective inhibition of COX-1, whose job is to protect the gastro-intestinal (GI) tract lining, can lead to dangerous side effects. Several newer drugs were developed that were more selective. But these drugs turned out to have even more severe side effects, potentially increasing the risk of heart attack and stroke. The problem was too much selectivity. By completely shutting down COX-2, these drugs may have shut down the production of blood-clotting hormones and other cardio-protective enzymes.

Whole Blood Assay Reveals Suprising Results

The William Harvey Whole Blood Assay is considered the "gold standard" for evaluating a compounds COX activity and selectivity. The goal was to find a botanical extract that could moderately inhibit the pain causing COX-2, while only mildly inhibiting the protective COX-1. The humulones extracted from hops fit this model perfectly. The extract inhibited COX-2 strongly enough to alleviate pain, without shutting down the enzyme altogether. And it only mildly inhibited COX-1 to avoid GI problems.
 

The Quest to Find a Plant-Derived Anti-Inflammatory Agent

Vinoprin One Hour Pain Relief contains a proprietary hops extract that is standardized to contain 150mg of humulones (alpha acids) - the active anti-inflammatory components - and designed to be free of phytoestrogenic and sleep inducing compounds. The extraction process utilizes high temperature, high pressure, liquid C02, to perform the extraction with NO toxic chemicals. During the late 1990s, several research companies began looking for natural ways to ease the pain of arthritis and other conditions. Hundreds of different botanicals were examined, and thousands of pages of scientific studies were reviewed. At the end of this painstaking process, about 20 candidates were identified for further study. All of the prospects, including higly regarded botanical agents such as curcumin and boswellia were subjected to in vitro testing to determine their anti-inflammatory potential. Of those, the hops extract was identified as having the highest chance of success.

 

Human Clinical Trials Confirm the Finding

These COX inhibition properties were confirmed on a group of healthy volunteers, with blood levels of COX enzymes measured over a 9 hour period. A double-blind efficacy study showed that hops extract provided significant pain relief vs. placebo to subjects suffering from pain. During the 14 day trial period, subjects were measured to have significant improvements in comfort while walking, standing, climbing stairs, and sleeping.

 

Bioavailability

In-vitro testing, utilizing the standard CACO-2 cell monolayer assay indicates that there is high permeability of the hops extract, which correlates with good human oral bioavailability.

Each Vinoprin One Hour Pain Relief softgel is standardized to contain at least 150mg of humulones (alpha acids), the active ingredient. In addition, small amounts of peppermint and ginger oils are added to counteract any possible GI upset. Vinoprin One Hour Pain Relief is non-GMO, free of milk, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten and soy. Hops (Humulus lupulus L.) 

What kind of pain can I use Vinoprin One Hour Pain Relief for?

Vinoprin One Hour Pain Relief is not a drug, and is not intended to treat any disease. However, Vinoprin One Hour Pain Relief is effective for almost all normal aches and pains in any part of the body.

How many Vinoprin One Hour Pain Relief softgels should I take?

We recommend that you start with two Vinoprin One Hour Pain Relief softgels with a meal early in the day for 8-12 hours of pain relief. If you have discomfort that is interfering with sleep, take one or two more with dinner.

Should I take Vinoprin One Hour Pain Relief with food?

When you start taking Vinoprin One Hour Pain Relief, you may experience some digestive side effects due to the bitterness of the hops. These effects are minimized by taking Vinoprin with food. 

Are there any interactions with other medications?

There are few known interactions with Vinoprin One Hour Pain Relief and medications (both prescription and over-the-counter). As a prudent precaution, please consult with your doctor if you are taking any prescription drugs.

Any known allergies?

Vinoprin One Hour Pain Relief contains one primary ingredient (Humulone extracted from hops) plus ginger oil and peppermint oil to settle the digestive system. A very small percentage of people may be allergic to one of these ingredients. In addition, Lecithin extracted from soy oil is used to prevent separation of ingredients. Vinoprin contains no other common allergens.

Any other questions?

Please feel free to contact us at 1-412-343-1802 Monday to Friday 9am to 5:45pm Eastern or E-mail us at: CS@Vinomis.com

Order with Confidence

Our products are unconditionally guaranteed and may be returned for any reason for 60 days from the original shipping date. We will refund the full price and any shipping you paid us for products that are returned to us during that time, including one open bottle. Please call customer service for an authorization number prior to sending back product so that we can process refunds without delay.

Send all returns to:
Vinomis Returns
99 Alfred Street Pittsburgh, Pa 15228 
Refunds will be made back to the credit card, bank account, PayPal account, or Amazon account that was used for the purchase.

Please note that shipping is not refundable on free sample packs. Customers are responsible for the return shipping and postage. We suggest that returns are sent using tracking. Vinomis is not responsible for lost return shipments.

Return Shipping
Return postage is the customer’s responsibility, and is non-refundable. We are not responsible for lost or damaged returns, and recommend that you use a traceable carrier that can provide delivery confirmation and insurance for your protection. Please include the return authorization number provided by our customer service representative to ensure a speedy refund.

Any questions?

We would love to hear from you or assist you in purchasing.

Please call us at 412-721-0484.

Email: Write us at: cs@vinomis.com

Business Hours: Monday to Friday: 9am - 5 pm Eastern